Tadaflo 20 mg (which contains the active ingredient tadalafil) can potentially interact with other medications. It's important to be cautious of potential drug interactions, as they can affect the effectiveness and safety of both Tadaflo 20 mg and the other medications you might be taking. Nitrates commonly used for chest pain (angina), can interact with tadalafil and cause a significant drop in blood pressure. Combining Tadaflo 20 mg with nitrates can lead to a potentially dangerous decrease in blood pressure. Alpha-Blockers Alpha-blockers, prescribed for conditions like high blood pressure and benign prostatic hyperplasia (enlarged prostate), can also lower blood pressure. Combining alpha-blockers with Tadaflo 20 mg online can increase the risk of hypotension (low blood pressure). Antihypertensives Medications used to lower blood pressure can interact with tadalafil and further lower blood pressure, potentially causing dizziness, lightheadedness, and other symptoms of low blood pressure. Certain Antifungal and Antibiotic Medications Some antifungal and antibiotic medications can affect the metabolism of tadalafil, potentially increasing its concentration in the body. Certain Cardiovascular Medications Medications that affect heart rate and rhythm, as well as medications used to treat pulmonary hypertension, can interact with tadalafil. Serotonin Modulators and Antidepressants Combining tadalafil with certain antidepressants and serotonin modulators can increase the risk of serotonin syndrome, a potentially serious condition. Before using Tadaflo 20 mg or any medication, it's crucial to consult a healthcare provider and provide a comprehensive list of all the medications you're taking. They can assess potential interactions, provide guidance, and recommend the best course of action to ensure your safety and well-being.